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Neuromyelitis Optica Presenting as Non-Communicating Hydrocephalus: A Case Report
Shalesh Rohatgi1, Prajwal Rao1, Satish Nirhale1
1Department of Neurology, Dr D Y Patil Medical College, Hospital and Research Center, Dr DY Patil Vidyapeeth Pune, Maharashtra, India.
Neurology India
|January 4, 2024
Summary
This case report details a rare instance of Neuromyelitis Optica (NMO) presenting with hydrocephalus in a 32-year-old female. Early diagnosis and treatment involving shunting and immunosuppression led to symptom improvement.
Area of Science:
- Neurology
- Immunology
- Neuro-ophthalmology
Background:
- Neuromyelitis Optica (NMO) is a severe autoimmune demyelinating disease targeting the central nervous system.
- Aquaporin-4 (AQP4) antibodies are key in NMO pathogenesis, primarily affecting optic nerves and the spinal cord.
- The co-occurrence of hydrocephalus with NMO is exceptionally rare.

