[A scientifically grounded pharmacological treatment of ADHD]
1Amsterdam UMC, locatie VUmc, Amsterdam.
Abstract:
Methylphenidate is the first-choice pharmaceutical treatment for children and adolescents with attention deficit/hyperactivity disorder (ADHD). Concerns have been raised regarding unnecessary or suboptimal prescription of this medicine. Based on the results of three recently conducted Dutch studies - the Medication Optimization for ADHD study (MOVA), the Methylphenidate Discontinuation Study in Children (MASK), and the Discontinuation Trials Study - we advocate for an evidence-based approach to the treatment of children and adolescents with methylphenidate. The studies highlight that careful assessment of the effects of methylphenidate using placebo-controlled titration and systematically evaluating long-term treatment through placebo-controlled discontinuation trials can be beneficial in reducing unnecessary prescriptions of methylphenidate.
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