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Screening for Colorectal Cancer: The Role of Clinical Laboratories
Joseph F Toth1, Mehul Trivedi1, Samir Gupta1,2,3
1Department of Internal Medicine, University of California San Diego Health, La Jolla, CA, United States.
Background:
Colorectal cancer (CRC) is a leading cause of cancer incidence and mortality. Screening can result in reductions in incidence and mortality, but there are many challenges to uptake and follow-up.
Content:
Here, we will review the changing epidemiology of CRC, including increasing trends for early and later onset CRC; evidence to support current and emerging screening strategies, including noninvasive stool and blood-based tests; key challenges to ensuring uptake and high-quality screening; and the critical role that clinical laboratories can have in supporting health system and public health efforts to reduce the burden of CRC on the population.
Summary:
Clinical laboratories have the opportunity to play a seminal role in optimizing early detection and prevention of CRC.
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