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Author Correction: Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data

Xi Chen1,2, Yuan Wang3, Antonio Cappuccio4

  • 1Center for Computational Biology, Flatiron Institute, New York, NY, USA.

Nature Computational Science
|January 4, 2024
PubMed
Summary

No abstract available in PubMed .

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Cis-regulatory Sequences

Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...