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Related Concept Videos

Teeth01:15

Teeth

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
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Tooth Anatomy01:21

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The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
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Related Experiment Video

Updated: Jul 6, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
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Association between life's essential 8 and periodontitis: a population-based study.

XingJin Chen1,2, JiangLing Sun2, ChongWen Zeng1,2

  • 1School of Stomatology, Zunyi Medical University, Zunyi, China.

BMC Oral Health
|January 4, 2024
PubMed
Summary

Higher scores on the American Heart Association's Life's Essential 8 (LE8) cardiovascular health metric were associated with a lower likelihood of developing periodontitis in American adults. This finding highlights a potential link between overall cardiovascular wellness and gum health.

Keywords:
Cross-sectional studyLife’s essential 8NHANESPeriodontitis

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Area of Science:

  • Cardiovascular Health
  • Periodontal Medicine
  • Public Health

Background:

  • The American Heart Association introduced Life's Essential 8 (LE8) as a novel cardiovascular health indicator.
  • No prior studies have investigated the association between LE8 and periodontitis.
  • This study addresses the gap by examining the relationship between LE8 and periodontitis in a US adult population.

Purpose of the Study:

  • To investigate the association between Life's Essential 8 (LE8) scores and the prevalence of periodontitis among American adults.
  • To determine if cardiovascular health, as measured by LE8, is linked to periodontal health.

Main Methods:

  • Utilized data from the National Health and Nutrition Examination Survey (NHANES) spanning 2009-2014.
  • Employed multivariable logistic regression models to analyze the relationship between LE8 (independent variable) and periodontitis (dependent variable).
  • Classified LE8 into high, moderate, and low grades and periodontitis based on Eke's 2012 criteria.

Main Results:

  • A total of 9,039 adults participated, with a mean age of 52.16 years; 50.48% had periodontitis.
  • A statistically significant negative correlation was found between LE8 scores and periodontitis (OR=0.98, P<0.001).
  • Individuals in the highest LE8 group showed a 47% reduced risk of periodontitis compared to the lowest group (OR=0.53, P<0.001).

Conclusions:

  • A significant negative association exists between higher Life's Essential 8 scores and the likelihood of periodontitis.
  • This cross-sectional study suggests that improved cardiovascular health may be linked to better periodontal health.
  • Findings indicate a potential role for LE8 in assessing overall health, including oral health outcomes.