Recent progress of covalent organic frameworks as attractive materials for solid-phase microextraction: A review

Area of Science:

• Materials Science
• Analytical Chemistry
• Separation Science

Background:

• Solid-phase microextraction (SPME) is a widely adopted green analytical technique for sample preparation.
• Covalent organic frameworks (COFs) are advanced porous materials with desirable properties like high surface area and stability.
• COFs show significant potential for enhancing SPME fiber coatings due to their unique characteristics.

Purpose of the Study:

• To review preparation methods for COF-based SPME coatings.
• To summarize applications of COF-SPME in environmental, food, and biological sample analysis.
• To discuss the advantages and challenges of using COF-SPME in practical settings.

Main Methods:

• Physical adhesion techniques for coating COFs onto SPME fibers.
• Sol-gel processes for creating robust COF-based SPME coatings.
• In situ growth and chemical cross-linking strategies for COF immobilization.
• Review of literature on COF synthesis and SPME applications.

Main Results:

• Various effective methods for preparing COF-SPME coatings have been developed.
• COF-SPME demonstrates successful preconcentration of diverse analytes in complex matrices.
• COF-based SPME offers improved extraction efficiency and selectivity compared to traditional methods.

Conclusions:

• COF-based SPME coatings represent a promising advancement in sample preparation.
• Further research is needed to overcome challenges for widespread practical adoption.
• COFs are valuable materials for developing next-generation analytical tools.