Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

3C suppresses PINK1-mediated mitophagy and contributes to coxsackievirus B3 replication.

Virulence·2026

Same author

AI-driven tissue discrimination sensing methods for robot-assisted spine surgery: a state-of-the-art review.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026

Same author

A new subtype of hepatitis E virus gene 3 has emerged in Italy and several other European countries.

The new microbiologica·2026

Same author

3D alginate hydrogel microspheres with uniform micro-structure for cell culture and CVB3 infection.

Mikrochimica acta·2026

Same author

U<sup>2</sup>AD: Uncertainty-based unsupervised anomaly detection framework for detecting T2 hyperintensity in MRI spinal cord.

Medical image analysis·2026

Same author

Erratum: MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4B<sup>DCAF13</sup> E3 Ligase in Osteosarcoma Cells.

Molecular therapy. Nucleic acids·2026

Same journal

Chemometric profiling reveals selective circulating bile acid remodeling in Alzheimer's disease.

Clinica chimica acta; international journal of clinical chemistry·2026

Same journal

Serum sialic acid is independently associated with cerebrovascular atherosclerotic stenosis severity and total vascular burden: A retrospective cohort study.

Clinica chimica acta; international journal of clinical chemistry·2026

Same journal

Measurement of low-density lipoprotein cholesterol and other circulating lipids in Brazil: a systematic literature review.

Clinica chimica acta; international journal of clinical chemistry·2026

Same journal

Reference intervals for venous blood gas measurement in a healthy Chinese population.

Clinica chimica acta; international journal of clinical chemistry·2026

Same journal

Multiplex methylation marker analysis for ctDNA detection in liquid biopsies from anal cancer patients: an HPV-independent approach.

Clinica chimica acta; international journal of clinical chemistry·2026

Same journal

Development and validation of patient-based exponentially weighted moving average quality control models for three antipsychotic drugs and their metabolites by LC-MS/MS.

Clinica chimica acta; international journal of clinical chemistry·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 6, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

Myocarditis: A multi-omics approach.

Lulu Wang¹, Tao Sun², Xiaolan Liu¹

¹School of Medicine, Jiangsu University, Zhenjiang 212013, Jiangsu, China.

Clinica Chimica Acta; International Journal of Clinical Chemistry

|January 6, 2024

Summary

This summary is machine-generated.

Understanding myocarditis (inflammation of the heart muscle) is crucial for preventing heart failure. This review highlights how multi-omics approaches, integrating genomics, transcriptomics, proteomics, and metabolomics, offer profound insights into disease development.

Keywords:

Genomics Metabolomics Multi-omics Myocarditis Proteomics Transcriptomics

More Related Videos

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Published on: June 20, 2014

Isolation and Identification of Extravascular Immune Cells of the Heart

Isolation and Identification of Extravascular Immune Cells of the Heart

Published on: August 23, 2018

Related Experiment Videos

Last Updated: Jul 6, 2025

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Published on: June 20, 2014

Isolation and Identification of Extravascular Immune Cells of the Heart

Isolation and Identification of Extravascular Immune Cells of the Heart

Published on: August 23, 2018

Area of Science:

Cardiology
Molecular Biology
Genetics

Background:

Myocarditis is a serious heart condition leading to heart failure and sudden death.
Traditional research methods have limitations in fully elucidating myocarditis pathogenesis.
Emerging omics technologies offer novel avenues for understanding complex diseases.

Purpose of the Study:

To review the role of various biomolecules and pathways in myocarditis pathogenesis using omics data.
To explore the reproducibility and variability challenges in omics studies.
To emphasize the significance of a multi-omics approach for comprehensive disease analysis.

Main Methods:

Systematic review of existing literature on omics studies in myocarditis.
Analysis of genomics, transcriptomics, proteomics, and metabolomics data.
Evaluation of functional pathways implicated in myocarditis development.

Main Results:

Omics data reveal critical biomolecules and pathways involved in myocarditis.
Variability and reproducibility issues in single-omic studies are identified.
A multi-omics strategy provides a more holistic and accurate view of myocarditis.

Conclusions:

Integrating multi-omics data is essential for a profound understanding of myocarditis pathogenesis.
A holistic approach enhances insights into disease mechanisms and biomarkers.
This strategy is critical for advancing myocarditis research and clinical applications.