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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
Published on: September 14, 2010
Kaposi's sarcoma of the larynx: case series
Mircea Sorin Ciolofan1, Florin Anghelina, Carmen Aurelia Mogoantă
1Department of Otorhinolaryngology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania; carmen_mogo@yahoo.com; Department of Otorhinolaryngology, Dr. Vlăescu Central Polyclinic, Craiova, Romania; alex.vlaescu@gmail.com.
Abstract:
Kaposi's sarcoma (KS) represents a type of cancer that usually arises on the skin and very rarely in other organs. KS-associated herpesvirus (KSHV), also known as human herpesvirus-8 (HHV-8) commonly arises in patients with acquired immunodeficiency syndrome (AIDS). Laryngeal involvement of KS is very rare. Our study comprised of three cases with laryngeal KS. All cases were solved through surgical excision of the tumor. Histopathological and immunohistochemistry examinations revealed laryngeal KS. Laryngeal KS should be managed through surgical resection, followed by oncological treatment.

