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Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
Published on: February 23, 2024
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Therapeutic Plasma exchange therapy in Burns
Padmalakshmi Bharathi Mohan1, Ravi Kumar Chittoria2, Shijina Koliyath1
1Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India.
Journal of Cutaneous and Aesthetic Surgery
|January 8, 2024
Summary
Severe burn injuries trigger systemic inflammation, leading to fluid loss and refractory hypotension. Therapeutic plasma exchange may help manage these severe burn complications.
Area of Science:
- Burn injury research
- Critical care medicine
- Inflammatory response
Background:
- Severe burn injuries induce systemic inflammatory response syndrome (SIRS).
- SIRS increases capillary permeability, causing significant fluid loss and refractory hypotension.
- Elevated inflammatory mediators, such as interleukin-6 (IL-6), exacerbate capillary leak and hypotension.
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