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Related Experiment Video

Updated: Jul 6, 2025

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

Published on: May 12, 2011

Ischemic optic neuropathy following craniotomy.

Ranjit Kumar Chaudhary¹, Sanjib Kumar Chaudhary², Elina Gupta³

¹Department of Radiology, Neuroradiology Division, University of Texas Medical Branch, Galveston, Texas, USA,.

Journal of Nepal Health Research Council

|January 10, 2024

Summary

This summary is machine-generated.

Ischemic optic neuropathy (ION) can cause severe vision loss. This case highlights a rare instance of ION in a young patient following brain surgery, emphasizing the need for awareness of this perioperative complication.

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The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION

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Last Updated: Jul 6, 2025

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System

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Published on: May 12, 2011

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells

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The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION

Published on: November 20, 2016

Area of Science:

Ophthalmology
Neurology
Vascular Surgery

Background:

Ischemic optic neuropathy (ION) is a significant cause of vision impairment and blindness.
Its etiopathogenesis is diverse, with limited therapeutic strategies and often poor prognoses.
Perioperative ION is uncommon, typically affecting elderly individuals with comorbidities undergoing major surgeries like cardiac or spinal procedures.

Observation:

This report details a rare case of ION in a young patient.
The complication occurred after a craniotomy procedure performed for a recurrent meningioma.

Findings:

The patient developed ischemic optic neuropathy following craniotomy.
This presentation is unusual given the patient's young age and the specific surgical context.

Implications:

This case underscores the importance of considering ION as a potential perioperative complication, even in younger patients.
Further research into the specific risk factors and mechanisms of ION in diverse surgical settings is warranted.
Early recognition and management strategies for perioperative ION may improve patient outcomes.