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Stillbirth and the placenta.

Jerri A Waller1, George Saade2

  • 1Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School.

Seminars in Perinatology
|January 10, 2024
PubMed
Summary
This summary is machine-generated.

Stillbirth remains a significant global health issue. This study details gross and histologic placental changes associated with stillbirth, aiding in understanding its causes.

Keywords:
Fetal vascular malperfusionIntrauterine fetal demiseMaternal vascular malperfusionPlacentaStillbirth

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Area of Science:

  • Perinatal Medicine
  • Pathology

Background:

  • Stillbirth is a major global public health concern, affecting numerous pregnancies annually.
  • Identified causes include obstetrical complications, placental abnormalities, fetal malformations, infections, and maternal medical conditions.
  • Placental abnormalities are frequently implicated in stillbirth, but placental changes can also be secondary to other etiologies.

Purpose of the Study:

  • To describe the gross and histologic changes observed in placentas from stillbirth cases.
  • To enhance the understanding of placental pathology in the context of stillbirth.

Main Methods:

  • Examination of gross placental morphology.
  • Histologic evaluation of placental tissues.

Main Results:

  • Detailed description of macroscopic placental findings in stillbirth.
  • Comprehensive analysis of microscopic placental alterations associated with stillbirth.

Conclusions:

  • Gross and histologic placental examination is crucial for identifying pathological changes.
  • Understanding these placental changes contributes to determining the etiology of stillbirth.