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Related Concept Videos

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Network Covalent Solids

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
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Biocompatible Hydrogel-Based Liquid Marbles with Magnetosomes.

Rafał Bielas1, Tomasz Kubiak1, Matus Molcan2

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Summary

Researchers developed versatile liquid marbles using plant-based coatings and magnetic properties for biomedical applications. These functionalized marbles can encapsulate substances and be magnetically controlled, offering new possibilities for drug delivery and hyperthermia treatments.

Keywords:
EPR spectroscopyagarhydrogelliquid marblesmagnetosomesmagnetotactic bacteriaturmeric particles

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Area of Science:

  • Materials Science
  • Biotechnology
  • Nanotechnology

Background:

  • Liquid marbles offer versatile platforms for biomedical applications due to their ease of preparation and unique properties.
  • Encapsulation and controlled manipulation of substances are crucial for advanced drug delivery and therapeutic strategies.

Purpose of the Study:

  • To develop novel liquid marbles with magnetic properties using biocompatible plant-based coatings.
  • To explore their potential for encapsulating various payloads and for applications in drug delivery and magnetic hyperthermia.

Main Methods:

  • Preparation of liquid marbles with cores of water, hydrogels, magnetic fluids, or non-aqueous substances.
  • Coating with biocompatible plant particles (turmeric, Lycopodium pollen).
  • Incorporation of magnetic properties using magnetosomes or iron oxide nanoparticles, verified by EPR spectroscopy and VSM.

Main Results:

  • Stable liquid marbles with tunable magnetic properties were successfully fabricated.
  • Hydrogel-core magnetic marbles showed potential as biocompatible heating agents under alternating magnetic fields.
  • Composite structures with distinct core and magnetic fluid layers were created.

Conclusions:

  • Liquid marbles, particularly hydrogel-core magnetic variants, demonstrate significant potential for biomedical use owing to their ease of preparation and favorable properties.
  • The ability to simultaneously produce, functionalize, and magnetically manipulate multiple marbles enhances their application prospects.