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Updated: Jul 5, 2025

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18F-FDG PET/CT in extranodal natural killer/T-cell lymphoma: a comprehensive evaluation method
Xiaoyue Zhang1, Wenpeng Huang1, Yongkang Qiu1
1Department of Nuclear Medicine, Peking University First Hospital Beijing 100034, PR China.
Abstract:
Extranodal NK/T-cell lymphoma (ENKTL) is an uncommon subtype of non-Hodgkin's lymphoma that is closely related to Epstein-Barr virus (EBV) infection. ENKTL exhibits distinctive clinicopathological features among lymphomas and has poor overall survival in the absence of effective treatment. The timely and accurate diagnosis of ENKTL is crucial for effective treatment and a positive prognosis. 18F-Fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG PET/CT) has emerged as an invaluable diagnostic modality for staging, curative effect evaluation, and prognosis analysis in ENKTL. We herein provide a comprehensive overview of the advances in the application of 18F-FDG PET/CT in patients with ENKTL.
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