[Pleomorphic adenocarcinoma of the pancreas with extrapancreatic proliferation]

Two cases of pleomorphic adenocarcinoma of the pancreas are reported. The patients were both women, aged 42 and 44, respectively. Their primary lesions had proliferated extrapancreatically and revealed a clinically specific patterns. They were differed from the general findings of pancreatic cancer. In the histological appearance, tissues such as well-differentiated adenocarcinoma and a mixture of giant cell carcinoma (osteoclastic type) and spindle cell sarcomatous type were seen, and they transferred in either. The extirpation of these tumors was possible, but they recurred in the short term and had an extremely unfavorable prognosis.