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Post-Hyaluronic Acid Filler Reaction Treated With Abrocitinib: A Case Report
Journal of Drugs in Dermatology : JDD
|January 11, 2024
Summary
Delayed-onset nodules after hyaluronic acid (HA) filler injections can be challenging. Oral abrocitinib showed significant improvement in a patient, suggesting it as a novel treatment for HA filler complications.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Pharmacology
Background:
- Post-hyaluronic acid (HA) filler nodules are rare but challenging complications.
- Delayed-onset nodules present a therapeutic dilemma.
Observation:
- A female patient in her fifties developed edema and nodules 6 weeks post-HA filler injection.
- Initial treatments with oral steroids and intralesional hyaluronidase provided minimal improvement.
Findings:
- A trial of oral abrocitinib was initiated for the persistent nodules.
- Significant clinical improvement was observed after initiating abrocitinib therapy.
Implications:
- Abrocitinib may represent a novel therapeutic option for managing delayed-onset nodules following HA filler injections.
- This case highlights a potential new treatment avenue for uncommon HA filler complications.
