Related Experiment Video

Updated: Jul 5, 2025

Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry
07:13

Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry

Published on: August 16, 2016

7.3K

Chemical Methods to Identify Epigenetic Modifications in Cytosine Bases

Madhumitha N1, Parvathy S Kumar1, Debasish Manna1

  • 1Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, Madhya Pradesh, India.

Chemistry, an Asian Journal
|January 11, 2024
PubMed

Keywords:
Cytosine 3Ten Eleven Translocation 5epigenetics 1methylation 2sequencing 4

More Related Videos

High Sensitivity 5-hydroxymethylcytosine Detection in Balb/C Brain Tissue07:19

High Sensitivity 5-hydroxymethylcytosine Detection in Balb/C Brain Tissue

Published on: February 1, 2011

15.1K
DNA Methylation: Bisulphite Modification and Analysis12:34

DNA Methylation: Bisulphite Modification and Analysis

Published on: October 21, 2011

105.0K

Related Concept Videos

Chromatin Immunoprecipitation- ChIP02:36

Chromatin Immunoprecipitation- ChIP

Chromatin immunoprecipitation, or ChIP, is an antibody-based technique used to identify sites on DNA that bind to transcription factors of interest or histone proteins. It also helps determine the type of histone modifications such as acetylation, phosphorylation, or methylation.
Types of ChIP
ChIP can be divided into two types - X-ChIP and N-ChIP. X-ChIP involves in vivo cross-linking of histones and regulatory proteins to DNA, fragmenting the DNA by sonication, and isolating the protein-DNA...
11.1K
Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
3.0K
Histone Modification02:32

Histone Modification

3.4K
Inheritance of Chromatin Structures03:17

Inheritance of Chromatin Structures

Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying...
6.3K