Modern methods and materials used to treat root perforation: effectiveness comparison

Area of Science:

• Endodontics
• Biomaterials Science
• Regenerative Dentistry

Background:

• Endodontic materials are crucial for sealing root canals and managing pulpitis and perforations.
• Evaluating new biomaterials for enhanced efficacy and regenerative potential is an ongoing need in dentistry.

Purpose of the Study:

• To experimentally compare the efficacy of iRoot BP Plus against other endodontic materials (Biodentine, MTA, Rootdent, Trioxide) in treating pulpitis and perforations.
• To investigate the influence of iRoot BP Plus on regenerative processes and restoration after pulp amputation in laboratory animals.

Main Methods:

• Micropermeability analysis of five endodontic biomaterials using 50 single-rooted teeth.
• Investigating molar morphology changes in rabbits after pulp removal and iRoot BP Plus treatment.

Main Results:

• iRoot BP Plus exhibited superior performance in retrograde apical root filling, showing a higher sealing effect compared to other materials.
• Animal studies indicated protective adaptive mechanisms, including inflammation, connective tissue replacement of necrosis, and intensive new capillary formation within 6 weeks post-treatment.

Conclusions:

• iRoot BP Plus provides hermetic sealing and good adhesion in tooth restoration.
• The material shows potential to actively promote tissue regeneration following pulp removal, suggesting a role in regenerative endodontics.