Photodynamic therapy for cutaneous inflammatory pseudotumour: A case report
Juan He1, Tengyu Weng1, Wei Ba1
1Department of Dermatology, First Medical Center of Chinese PLA General Hospital, Beijing, 100853, PR China.
Photodiagnosis and Photodynamic Therapy
|January 11, 2024
Summary
This case report details a rare instance of recalcitrant cutaneous inflammatory pseudotumour (IP) in an adult male. 5-aminolevulinic acid photodynamic therapy (ALA-PDT) showed promising results in reducing symptoms.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Inflammatory pseudotumour (IP) is a rare proliferative disease typically affecting the lungs in younger individuals.
- Cutaneous IP is exceptionally rare, with limited published cases, presenting a diagnostic and therapeutic challenge.
Observation:
- A 62-year-old male presented with an 8-year history of recalcitrant cutaneous IP.
- The patient showed poor response to conventional treatments including topical glucocorticoids and intralesional injections.
Findings:
- Four sessions of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) led to significant reduction in erythema and nodules.
- This suggests ALA-PDT's efficacy in managing difficult cutaneous IP cases.
Implications:
- ALA-PDT emerges as a potentially safe and effective therapeutic option for cutaneous inflammatory pseudotumour.
- Further research is warranted to establish ALA-PDT's role in treating this rare condition.


