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Updated: Jul 5, 2025
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Bronchoalveolar Lavage Exosomes in Lipopolysaccharide-induced Septic Lung Injury
Published on: May 21, 2018
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[Shenfu Injection alleviates sepsis-associated lung injury by regulating HIF-1α]
Luan-Luan Zhang1, Ya-Nan Zi1, Ye-Peng Zhang1
1Emergency Department, the First Affiliated Hospital of Zhengzhou University Zhengzhou 450000, China.
Summary
Shenfu Injection (SFI) protects against sepsis-associated lung injury by promoting mitophagy and improving mitochondrial function. This effect is mediated by regulating hypoxia-inducing factor-1α (HIF-1α) and enhancing autophagy.
Area of Science:
- Critical Care Medicine
- Pharmacology
- Cell Biology
