Post-translational modulation of cell signalling through protein succinylation

Katharina F Kubatzky1,2, Yue Gao1,2, Dayoung Yu1,2

  • 1Department of Infectious Diseases, Medical Faculty Heidelberg, Medical Microbiology and Hygiene, Heidelberg University, 69120 Heidelberg, Germany.

Summary

Cells use post-translational modifications (PTMs) to regulate protein activity. This review focuses on succinylation, a PTM where tricarboxylic acid cycle metabolites modify proteins, impacting health and disease.

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