Establishing a robust radioligand therapy program: A practical approach for North American centers

Area of Science:

• Oncology
• Nuclear Medicine

Background:

• Radioligand therapy (RLT) is an established targeted cancer treatment.
• RLT has demonstrated safety and efficacy in various cancers, including neuroendocrine tumors, lymphoma, and advanced prostate cancer.
• Current patient access to RLT in the United States is inconsistent.

Purpose of the Study:

• To provide practical recommendations for establishing and implementing robust radioligand therapy programs.
• To address the need for standardized RLT delivery as new therapies emerge.
• To outline requirements and considerations for RLT program implementation in North American centers.

Main Methods:

• Review of experience in establishing RLT programs in diverse settings.
• Development of recommendations based on practical implementation insights.
• Identification of minimal and optimal requirements for RLT programs.

Main Results:

• Practical recommendations for building and implementing RLT programs are presented.
• Considerations for system integration and special issues are discussed.
• Guidelines for minimal and optimal RLT program requirements are outlined.

Conclusions:

• Expansion of RLT programs is essential to improve and standardize patient access.
• The recommendations aim to facilitate the successful implementation of RLT services.
• Addressing system considerations and specific challenges is key for robust RLT program development.