Practical Considerations for Prostate Cancer Imaging and Radiopharmaceutical Therapy

Area of Science:

• Oncology
• Nuclear Medicine
• Radiopharmaceutical Therapy

Background:

• Prostate cancer management is evolving with targeted radiopharmaceutical therapies.
• Prostate-specific membrane antigen (PSMA)-targeted agents are key drivers of this advancement.
• Existing clinical workflows require adaptation to integrate these new therapies.

Purpose of the Study:

• To describe a practice-based approach for PSMA-targeted radiopharmaceutical therapy in prostate cancer.
• To detail operational components for seamless patient care across the clinical spectrum.
• To provide practical solutions for common challenges in delivering these advanced therapies.

Main Methods:

• Review of a practice-based workflow for prostate cancer radiopharmaceutical therapy.
• Analysis of key operational components: radiopharmaceutical selection, imaging, scheduling, staffing, safety, and delivery.
• Identification and discussion of common challenges and their solutions.

Main Results:

• A structured workflow is presented, covering patient referral to therapy administration.
• Essential operational elements for successful implementation are detailed.
• Practical strategies for overcoming implementation hurdles are provided.

Conclusions:

• Coordinated, high-quality care is achievable through optimized workflows for PSMA-targeted radiopharmaceutical therapy.
• This approach supports multidisciplinary care teams in managing prostate cancer patients.
• Effective operational planning is crucial for the successful integration of advanced radiopharmaceutical treatments.