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Updated: Aug 4, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Versatile applications of 3-OxoGlycals: A review
1Roger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, IL, 61801, USA.
3-Oxoglycals are versatile building blocks for synthesizing diverse organic molecules, including rare sugars and biologically active compounds. Their ease of use and accessibility make them valuable tools in glycochemistry and organic synthesis.
Area of Science:
- Organic Chemistry
- Carbohydrate Chemistry
- Bio-organic Chemistry
Background:
- 3-Oxoglycals are versatile synthons in organic synthesis.
- They are fundamental building blocks for constructing complex organic structures.
Approach:
- This review highlights the synthetic utility of 3-oxoglycals.
- Focuses on their application in creating diverse molecular architectures.
Key Points:
- 3-Oxoglycals facilitate the synthesis of rare sugars, N-inserted compounds, heterocycles, and polycyclic molecules.
- Synthesized compounds can exhibit significant biological activities or valuable photophysical properties.
- Reactions are simple, use readily available materials, and occur under mild conditions.
Conclusions:
- 3-Oxoglycals are valuable and accessible building blocks for novel molecule synthesis.
- Their versatility benefits various scientific fields, including glycochemistry and medicinal chemistry.
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