Related Experiment Video
Updated: Jul 5, 2026
Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
Published on: May 7, 2019
Longitudinally extensive transverse myelitis, a disabling disorder with a good prognosis: a case series from Nepal
Bishal Dhakal1, Kanchan Bogati2, Sunil Baniya2
1Bardibas Field Hospital.
Introduction:
Longitudinally extensive transverse myelitis (LETM) is a rare spinal cord disorder with variable etiologies and presentations. It can present solely or as an association with other neurological disorders.
Methodology:
It was a series of cases of LETM in a tertiary care hospital.
Clinical Presentation And Outcomes:
The initial three cases presented with bilateral lower extremity weakness and were diagnosed as transverse myelitis while, the fourth case, already diagnosed as LETM presented with seizure followed by loss of consciousness. All four cases had a good prognosis to date with continued physiotherapy.
Conclusion:
The early diagnosis of the disease helps to guide the optimal management and decide the potential need for physiotherapy.
Insights
Longitudinally extensive transverse myelitis (LETM) is a rare spinal cord disorder. Early diagnosis and physiotherapy are key for managing LETM, with cases showing good prognoses.
Area of Science:
- Neurology
- Immunology
Background:
- Longitudinally extensive transverse myelitis (LETM) is a rare spinal cord disorder.
- LETM presents with variable etiologies and clinical manifestations.
- It can occur independently or alongside other neurological conditions.
Purpose of the Study:
- To report a series of longitudinally extensive transverse myelitis cases.
- To highlight diagnostic and management strategies for LETM.
- To emphasize the importance of early intervention and physiotherapy.
Main Methods:
- Retrospective case series.
- Analysis of four patients diagnosed with LETM at a tertiary care hospital.
- Review of clinical presentations, diagnostic workups, and treatment outcomes.
Main Results:
- Three cases presented with bilateral lower extremity weakness, diagnosed as transverse myelitis.
- One case, with a prior LETM diagnosis, experienced seizures and loss of consciousness.
- All four patients demonstrated good prognoses with ongoing physiotherapy.
Conclusions:
- Early diagnosis of LETM is crucial for effective management.
- Physiotherapy plays a significant role in the recovery and prognosis of LETM patients.
- LETM management requires a tailored approach based on individual presentation.
