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Updated: Aug 15, 2026

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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
[Biological evaluation of Cuban plants. III]
Revista Cubana De Medicina Tropical
|January 1, 1979
Summary
Carica papaya leaf extracts demonstrate significant antimicrobial activity against clinically relevant bacteria. This study explored various plant extracts, identifying papaya as a potent natural antimicrobial agent.
Area of Science:
- Pharmacognosy
- Microbiology
- Ethnobotany
Context:
- Rising antimicrobial resistance necessitates novel therapeutic strategies.
- Natural products offer a promising source for new antimicrobial agents.
- Environmental bacteria pose clinical challenges.
Purpose:
- To evaluate the antimicrobial potential of plant extracts from various families.
- To identify effective antimicrobial compounds from natural sources.
- To assess activity against clinically significant bacteria.
Summary:
- Aqueous, alcoholic, and ketonic extracts from Martiniaceae, Caricaceae, Umbeliferae, Nictaginaceae, and Fitolacaceae species were tested.
- The gel double-layer diffusion method was employed for antimicrobial testing.
- Carica papaya leaf extracts exhibited the most significant antimicrobial action.
Impact:
- Highlights Carica papaya as a valuable source of natural antimicrobials.
- Provides a basis for further research into papaya-derived antimicrobial compounds.
- Contributes to the search for alternative treatments against bacterial infections.

