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[Patterns of drug resistance in Staphylococcus aureus from human clinical isolates]
N M Rojas Hernández1, N Fernández López, M H Espino Hernández
1Universidad de la Habana Facultad de Biología.
Abstract:
Fifty circulating strains of Staphylococcus aureus of clinical origin were characterized by their drug susceptibility to 15 antimicrobials through the method of radial diffusion in Mueller Hinton medium. Also, beta-lactam production was determined by acidimetric and chromogenic methods as well as the presence of methicillin-resistant strains. It was confirmed that 32% of strain was susceptible to tested antimicrobials, the most effective of which were imipenem, norfloxacyn, and amikacyn for 98, 96 and 92% susceptibility respectively. Twenty-seven different drug resistance patterns were found in the studied strains. 22% of the total strains was beta-lactam producers whereas 27% of the latter turned out to be methicilline-resistant.