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[Acid-base equilibrium in experimental acid indigestion in cattle]
Polskie Archiwum Weterynaryjne
|January 1, 1986
Summary
Rumen acidosis in heifers, induced by sugar, causes partially compensated metabolic acidosis. Kidney function plays a key role in correcting this acid-base imbalance.
Area of Science:
- Veterinary Medicine
- Animal Physiology
- Biochemistry
Context:
- Rumen acidosis is a common metabolic disorder in ruminants.
- Dietary changes, such as high sugar intake, can precipitate this condition.
- Understanding the acid-base disturbances is crucial for effective treatment.
Purpose:
- To investigate the blood and urine acid-base parameters in heifers with experimentally induced rumen acidosis.
- To characterize the metabolic acidosis and its compensation mechanisms.
- To evaluate the role of renal function in acid-base balance during acidosis.
Summary:
- Intraruminal sugar infusion in heifers induced partially compensated metabolic acidosis, with significant changes in blood pH, bicarbonate, and base excess within 24 hours.
- Peak changes in acid-base parameters occurred within the first 48 hours, coinciding with increased lactic acid.
- Acid-base disturbances lasted 4-9 days, with urine pH and renal acid excretion indicating a significant role of the kidneys in recovery.
Impact:
- Provides insights into the pathophysiology of sugar-induced rumen acidosis in cattle.
- Highlights the diagnostic significance of blood and urine acid-base parameters.
- Emphasizes the compensatory role of renal excretion in managing metabolic acidosis in ruminants.