Magnetic localisation of a current dipole implanted in dogs

In order to evaluate the difficulty in localising a current dipole due to volume conductor current contributions to the magnetocardiogram, accuracy of depth localisation of a commercial coaxial pacemaker cable, used as a current dipole, was studied in two experimental situations: immersed in a prismatic container with NaCl solution and introduced into the lower oesophagus of dogs. Isofield contour maps were obtained by interpolation of the magnetic field measured over a plane and perpendicular to it with a third-order gradiometer coupled to a SQUID. The dipole can be accurately localised in the prismatic container. The observation of an isofield map that is symmetric about the maximum-minimum axis when the dogs are in the dorsal decubitus position with the dipole in the cephalocaudal direction implies that internal inhomogeneities in the dog's volume conductor produce no appreciable effect on the magnetic field. Nevertheless, a large distortion of the magnetic field lines is observed and can be explained by calculations using models that take into account the external boundary of the volume conductor.