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A four-cell pathway orchestrated by Flt3-L-dependent cDCs controls anti-tumor responses

Konstantinos Aliazis1, Vassiliki A Boussiotis1

  • 1Division of Hematology-Oncology, Boston, MA 02115, USA; Department of Medicine, Boston, MA 02115, USA; Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.

Cell Reports. Medicine
|January 17, 2024
PubMed
Summary

Flt3-ligand (FL) levels dictate anti-tumor immunity. Low FL levels promote T-cell responses, while high FL levels enhance natural killer (NK) cell and dendritic cell-mediated immunity.

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