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Identification of a myofibroblast differentiation program during neonatal lung development

Yongjun Yin1, Jeffrey R Koenitzer2, Debabrata Patra1

  • 1Departments of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110.

Biorxiv : the Preprint Server for Biology
|January 18, 2024
PubMed
Summary

This study identifies new mesenchymal cell subtypes in neonatal lungs, including a progenitor cell that develops into alveolar myofibroblasts (MyoFB). These findings clarify lung development and myofibroblast differentiation.

Keywords:
Adventitial fibroblastAlveologenesisLipofibroblastMatrix fibroblastMyofibroblastSecondary septaSingle cell genomic analysis

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