Enantioselective synthesis of [1,1'-binaphthalene]-8,8'-diyl bis(diphenylphosphane) and its derivatives
Yao Tang1, Qingkai Yuan1, Sai Zhang1
1Department of Chemistry and Biochemistry, Texas Tech University Lubbock Texas 79409-1061 USA guigen.li@ttu.edu.
Abstract:
Two 8,8' disubstituted binaphthyl ligands have been designed and synthesized in 3.1% and 11.4% overall yield, respectively. X-ray structure analysis demonstrated that a unique chiral microenvironment was created. With the assistance of a new aggregation-induced polarization (AIP) technology, chiral aggregates were determined as the fraction of polar solvent increased in the nonpolar/polar solvent system, which indicated their potential in modern asymmetric synthesis and catalysis.
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