An Interpretable Approach with Explainable AI for Heart Stroke Prediction

Parvathaneni Naga Srinivasu1,2, Uddagiri Sirisha2, Kotte Sandeep3

  • 1Department of Teleinformatics Engineering, Federal University of Ceará, Fortaleza 60455-970, Brazil.

PubMed

Insights

This study presents an interpretable Artificial Neural Network (ANN) model for accurate heart stroke prediction. Using explainable AI, the model achieves 95% accuracy, enhancing clinical decision-making for heart disease.

Area of Science:

  • Medical Informatics
  • Machine Learning in Healthcare
  • Artificial Intelligence for Disease Prediction

Background:

  • Heart strokes pose a significant global health challenge.
  • Existing machine learning (ML) models for stroke prediction often lack clinical interpretability.
  • Healthcare professionals require understandable AI tools for critical decision-making.

Purpose of the Study:

  • To develop an effective and interpretable heart stroke prediction model using explainable AI (XAI).
  • To address the gap between complex ML models and their clinical applicability.
  • To provide a reliable and understandable tool for healthcare practitioners.

Main Methods:

  • Utilized the Stroke Prediction Dataset with 11 attributes.
  • Implemented data preprocessing techniques: resampling, data leakage prevention, and feature selection.
  • Employed explainable AI methods: permutation importance and LIME for model interpretability.

Main Results:

  • Achieved an outstanding accuracy rate of 95% for heart stroke prediction.
  • Permutation importance provided global feature insights.
  • LIME offered local, instance-specific explanations, enhancing Artificial Neural Network (ANN) model comprehension.

Conclusions:

  • The developed ANN model offers a reliable and interpretable solution for heart stroke prediction.
  • Explainable AI techniques significantly improve the clinical utility of predictive models.
  • This approach can enhance healthcare decision-making and patient outcomes in cardiovascular health.