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Microbial Corrosion01:24

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Copper Materials for Caries Management: A Scoping Review.

Veena Wenqing Xu1, Mohammed Zahedul Islam Nizami1,2, Iris Xiaoxue Yin1

  • 1Faculty of Dentistry, University of Hong Kong, Hong Kong, China.

Journal of Functional Biomaterials
|January 22, 2024
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Copper materials show antimicrobial properties effective against cavity-causing bacteria and fungi. These materials, including copper alloys, salts, and oxides, can be integrated into dental products and even food for caries prevention.

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Area of Science:

  • Dental Materials Science
  • Antimicrobial Agents
  • Public Health

Background:

  • Dental caries remains a significant global health issue.
  • Caries management strategies are continuously evolving.
  • Antimicrobial agents offer a promising avenue for caries prevention.

Purpose of the Study:

  • To comprehensively review copper materials for caries management.
  • To categorize types, properties, and applications of copper materials.
  • To assess the potential of copper materials in preventing dental caries.

Main Methods:

  • Systematic literature search of PubMed, Scopus, and Web of Science.
  • Screening of titles and abstracts for original studies.
  • Inclusion of 34 publications on copper materials.

Main Results:

  • Copper materials (alloys, salts, oxides) demonstrated inhibition of cariogenic bacteria (e.g., Streptococcus mutans) and Candida albicans.
  • Potential applications include incorporation into topical agents, dental materials, drinking water, and sugar.
  • The majority of reviewed studies (83%) were laboratory-based, with limited animal (14%) and clinical (3%) research.

Conclusions:

  • Copper materials possess significant antimicrobial properties against key cariogenic microorganisms.
  • Incorporation into various products offers novel strategies for caries prevention.
  • Further clinical research is crucial to validate the efficacy and safety of copper-based caries management interventions.