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Related Concept Videos

Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

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Related Experiment Video

Updated: Jul 23, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
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Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

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Transcatheter Aortic Valve Replacement: Current Status and Future Indications.

Manish Vinayak1, Pier Pasquale Leone1, Richard Tanner1

  • 1Mount Sinai Heart, Mount Sinai Hospital, New York, NY 10029, USA.

Journal of Clinical Medicine
|January 23, 2024
PubMed
Summary

Transcatheter aortic valve replacement (TAVR) is now standard care for aortic stenosis, showing improved safety and fewer complications. TAVR is increasingly used in younger, lower-risk patients with longer life expectancies.

Keywords:
aortic stenosisaortic valve replacementtranscatheter aortic valve replacement

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Aortic stenosis management has been revolutionized by transcatheter aortic valve replacement (TAVR).
  • TAVR has become the standard of care across all surgical risk levels.
  • Significant advancements have enhanced TAVR safety and efficacy over the past two decades.

Purpose of the Study:

  • To provide an updated review of transcatheter aortic valve replacement (TAVR).
  • To discuss innovations in TAVR delivery systems and devices.
  • To explore potential future indications for TAVR.

Main Methods:

  • Review of recent advancements in TAVR technology and clinical applications.
  • Analysis of trends in TAVR safety, complications, and patient selection.
  • Synthesis of current literature on TAVR innovations and future directions.

Main Results:

  • TAVR demonstrates increasing safety and declining procedural complications.
  • Innovations in valve design, imaging, and operator expertise drive TAVR improvements.
  • TAVR is expanding to younger, lower-risk populations with longer life expectancies.

Conclusions:

  • Transcatheter aortic valve replacement (TAVR) continues to evolve as a primary treatment for aortic stenosis.
  • Ongoing innovations promise to further expand TAVR's role and indications.
  • The trend towards TAVR in lower-risk patients highlights its growing importance in cardiovascular medicine.