Related Experiment Video
Updated: Jul 5, 2025

Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis
Published on: June 18, 2020
Unveiling the predictive power: a comprehensive study of machine learning model for anticipating chronic kidney
Nitasha Khan1, Muhammad Amir Raza2, Nayyar Hussain Mirjat3
1Department of Electrical Engineering, Nazeer Hussain University, Karachi, Pakistan.
Abstract:
In today's modern era, chronic kidney disease stands as a significantly grave ailment that detrimentally impacts human life. This issue is progressively escalating in both developed and developing nations. Precise and timely identification of chronic kidney disease is imperative for the prevention and management of kidney failure. Historical methods of diagnosing chronic kidney disease have often been deemed unreliable on several fronts. To distinguish between healthy individuals and those afflicted by chronic kidney disease, dependable and effective non-invasive techniques such as machine learning models have been adopted. In our ongoing research, we employ various machine learning models, encompassing logistic regression, random forest, decision tree, k-nearest neighbor, and support vector machine utilizing four kernel functions (linear, Laplacian, Bessel, and radial basis kernels), to forecast chronic kidney disease. The dataset used constitutes records from a case-control study involving chronic kidney disease patients in district Buner, Khyber Pakhtunkhwa, Pakistan. For comparative evaluation of the models in terms of classification and accuracy, diverse performance metrics, including accuracy, Brier score, sensitivity, Youden's index, and F1 score, were computed.
Related Concept Videos
Nephrons
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Internal Anatomy of the Kidney
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...

