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Regression of Cardiac Lymphoma With Chemotherapy
Juan Fernández-Martínez1, Martín Descalzo-Buey1, Irene Menduiña-Gallego1
1Department of Cardiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Insights
Chest pain and myocardial changes in a patient were linked to lymphoma. Positron emission tomography and computed tomography revealed hypermetabolism and adenopathies. Chemotherapy led to regression of hypertrophy and edema.
Area of Science:
- Cardiology
- Oncology
- Radiology
Background:
- Chest pain and electrocardiographic changes are common presenting symptoms requiring thorough investigation.
- Cardiac magnetic resonance (CMR) and combined positron emission tomography-computed tomography (PET-CT) are advanced imaging modalities for cardiac and oncologic evaluation.
Observation:
- A patient presented with chest pain and electrocardiographic abnormalities.
- Cardiac magnetic resonance imaging revealed focal myocardial hypertrophy attributed to edema.
- Combined PET-CT demonstrated myocardial hypermetabolism and multiple adenopathies.
Findings:
- Biopsy confirmed the adenopathies were consistent with lymphoma.
- The patient's myocardial hypertrophy and edema showed significant regression following chemotherapy.
Implications:
- This case highlights the utility of integrated imaging techniques (CMR and PET-CT) in diagnosing complex cardiac conditions.
- It underscores the importance of considering systemic diseases like lymphoma in the differential diagnosis of myocardial abnormalities.
- Successful chemotherapy treatment indicates a potential therapeutic target for lymphoma-induced cardiac manifestations.
Abstract:
A patient was admitted for chest pain with electrocardiographic changes, and cardiac magnetic resonance showed focal myocardial hypertrophy secondary to edema. Combined positron emission tomography and computed tomography corroborated foci of myocardial hypermetabolism, as well as multiple adenopathies consistent with lymphoma in the biopsy. Hypertrophy and edema regressed with chemotherapy.
