Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 5, 2025

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies
09:51

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies

Published on: January 27, 2023

1.7K

Hepatic Sarcoidosis: Lesson Based on a Case Report.

Renato Farina1, Mariangela Clemenza1, Santo Riccardo Borzì1

  • 1Department of Surgical and Medical Sciences, Advanced Technologies GF Ingrassia, University of Catania, Catania, Italy.

Journal of Medical Ultrasound
|January 24, 2024
PubMed
Summary

Sarcoidosis, a multisystemic disease, can affect the liver, often presenting asymptomatically with elevated liver enzymes. Diagnosis is challenging, typically requiring histological confirmation of noncaseous granulomas.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uterine artery embolization for the treatment of symptomatic adenomyosis: a systematic review.

CVIR endovascular·2026
Same author

Measuring the Vein, Missing the Circuit: Gonadal Vein Diameter in Pelvic Venous Disorders.

Cardiovascular and interventional radiology·2026
Same author

Acute Non-Traumatic Urinary Tract Emergencies: The Central Role of CT Imaging and the Emerging Role of Photon-Counting CT.

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes·2026
Same author

Cerebral fat embolism syndrome in sickle cell disease: a case highlighting the predominance of susceptibility-weighted imaging findings and literature review.

Radiology case reports·2026
Same author

Lipoid Pneumonia: HRCT and MRI Spectrum, Diagnostic Pitfalls, and Imaging-Based Diagnostic Workflow.

Diagnostics (Basel, Switzerland)·2026
Same author

Beyond the clot: diagnostic yield, biomarker performance, and the landscape of alternative diagnoses in emergency CT pulmonary angiography.

Emergency radiology·2026

Area of Science:

  • Immunology
  • Gastroenterology
  • Pathology

Background:

  • Sarcoidosis is a multisystemic inflammatory disease of unknown cause, frequently affecting the lungs but potentially involving multiple organs.
  • Hepatic sarcoidosis is uncommon, with lesions that can mimic metastases, complicating diagnosis.
  • The disease typically presents in adults aged 20-40 and is characterized by noncaseous granulomas.

Observation:

  • This case involves an asymptomatic patient with elevated liver enzymes, indicative of hepatic sarcoidosis.
  • Imaging modalities like ultrasound, CT, MRI, and PET/CT are crucial for localizing lesions.
  • Histological examination is paramount for definitive diagnosis, differentiating sarcoidosis from other conditions.

Findings:

  • Elevated angiotensin-converting enzyme (ACE) levels, hypercalcemia, and hypercalciuria are common biochemical markers.
Keywords:
Computed tomographyhepatic sarcoidosismagnetic resonance imagingsarcoidosisultrasound

More Related Videos

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
00:06

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

8.9K
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

19.9K

Related Experiment Videos

Last Updated: Jul 5, 2025

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies
09:51

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies

Published on: January 27, 2023

1.7K
An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
00:06

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

8.9K
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

19.9K
  • Liver enzyme alterations occur in 35%-40% of sarcoidosis cases.
  • Granulomatous inflammation can progress to fibrosis, potentially leading to cirrhosis or portal hypertension in severe hepatic sarcoidosis.

    • Implications:

    • Early diagnosis and management of hepatic sarcoidosis are crucial to prevent disease progression and complications.
    • Understanding the diverse presentations of sarcoidosis is vital for accurate differential diagnosis.
    • Further research into the etiology and pathogenesis of sarcoidosis may improve diagnostic and therapeutic strategies.