Related Experiment Video
Updated: Jul 5, 2025

Intravascular Delivery of Biologics to the Rat Kidney
Published on: September 1, 2016
Extended-release buprenorphine in pregnancy
Alexander Hubbell1, Ese Aghenta2, Cresta Jones3
1M Health Fairview Addiction Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Background And Objectives:
The relative safety and efficacy of monthly extended-release buprenorphine (XR-BUP) has not been fully evaluated in pregnant persons.
Methods:
Case report of two pregnant individuals receiving XR-BUP while pregnant.
Results:
Both patients had positive experiences and healthy infants.
Discussion And Conclusions:
Sparse data regarding the use of XR-BUP in pregnant patients limits shared decision-making. Additional evidence will support the growing population of pregnant patients exposed to XR-BUP.
Scientific Significance:
Positive patient experiences using XR-BUP during pregnancy have been previously unreported. This report will contribute to discussions of risks and benefits for future patients using XR-BUP during pregnancy.
More Related Videos
Related Concept Videos
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Drugs for Treatment of Constipation-Predominant IBS
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Opioid Receptors: Overview
Factors Affecting Drug Response: Overview
Drug Delivery: Parenteral Route
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...

