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Extended-release buprenorphine in pregnancy.
Alexander Hubbell1, Ese Aghenta2, Cresta Jones3
1M Health Fairview Addiction Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
The American Journal on Addictions
|January 24, 2024
Summary
Monthly extended-release buprenorphine (XR-BUP) use during pregnancy resulted in positive patient experiences and healthy infants in a case report. Further research is needed to fully evaluate XR-BUP safety and efficacy in pregnant populations.
Area of Science:
- Obstetrics and Gynecology
- Addiction Medicine
- Pharmacology
Background:
- The safety and efficacy of monthly extended-release buprenorphine (XR-BUP) during pregnancy remain under-evaluated.
- Limited data hinders informed decision-making for pregnant individuals considering XR-BUP treatment.
Observation:
- This case report details the experiences of two pregnant individuals undergoing XR-BUP treatment.
- Both individuals received XR-BUP throughout their pregnancies.
Findings:
- Both patients reported positive experiences with XR-BUP therapy.
- Both patients delivered healthy infants, suggesting favorable outcomes.
Implications:
- This report contributes valuable, previously unreported data on XR-BUP use in pregnancy.
- Findings support further investigation into XR-BUP for pregnant patients with opioid use disorder.
- This evidence can aid clinicians and patients in risk-benefit discussions regarding XR-BUP during gestation.
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