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Neonatal Dermatopathology: A 10-Year Institutional Review
Allie Preston1,2, Cynthia Lee3, Martin Fernandez1
1Department of Pathology, Baylor Scott and White Health, Temple, TX, USA.
Fetal and Pediatric Pathology
|January 25, 2024
Summary
Neonatal skin biopsies are uncommon, with inflammatory and congenital conditions being the most frequent reasons for evaluation. This study reviews the spectrum of skin conditions requiring biopsy in newborns.
Area of Science:
- Dermatology
- Neonatology
- Pathology
Background:
- Neonatal skin conditions are usually diagnosed noninvasively.
- Limited data exists on biopsy-evaluated neonatal skin lesions.
- This study details institutional experience with skin biopsies in neonates.
Approach:
- Retrospective review of 20 neonatal skin biopsies over 10 years.
- Biopsies categorized into inflammatory, congenital, neoplastic, infectious, and vascular conditions.
- Analysis of patient demographics and lesion types.
Key Points:
- Patients ranged from 1 day to 4 weeks old, with a male predominance.
- Inflammatory (6) and congenital (7) lesions were most common.
- Neoplastic (5), infectious (1), and vascular (1) lesions were also identified.
Conclusions:
- Inflammatory and congenital conditions are the most frequent indications for neonatal skin biopsy.
- This review provides insight into neonatal dermatopathology specimens encountered in practice.
- Understanding these patterns aids in diagnosis and management of neonatal skin conditions.
