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An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy
Published on: October 21, 2014
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Editorial: Global excellence in cellular neuropathology: Ukraine
Andrii Cherninskyi1, Dirk M Hermann2, Elena Lukyanetz3
1Department of Cellular Membranology, Bogomoletz Institute of Physiology, Kyiv, Ukraine.
Frontiers in Cellular Neuroscience
|January 25, 2024
Summary
No abstract available in PubMed .
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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...

