Related Experiment Video
Updated: Jul 5, 2025

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
Published on: May 3, 2018
Visit-to-Visit Blood Pressure Variability in Cardiovascular Disease
Mifetika Lukitasari1, Siaw-Teng Liaw1, Bin Jalaludin1
1School of Population Health, UNSW Sydney, NSW 2052 Australia.
Insights
Visit-to-visit blood pressure variability (BPV) impacts cardiovascular disease (CVD) risk. Studies using electronic health records (EHR) and clinical trials show differences in data collection and BPV measurement metrics.
Area of Science:
- Cardiovascular Medicine
- Health Informatics
- Clinical Research Methodology
Background:
- Visit-to-visit blood pressure variability (BPV) is a recognized risk factor for cardiovascular disease (CVD), independent of average blood pressure (BP).
- In routine clinical practice, BPV is often overlooked and treated as random fluctuation rather than a significant clinical indicator.
- Discrepancies exist in how BPV is assessed and interpreted across different data sources.
Conclusions:
- The variability in data collection and BPV metrics poses challenges in comparing findings across studies.
- Standardization of BP measurement protocols and BPV estimation metrics is crucial for accurate CVD risk assessment.
- Further research is needed to establish consistent methodologies for evaluating BPV in real-world clinical settings.
Abstract:
Visit-to-visit blood pressure variability (BPV) is associated with cardiovascular disease (CVD), independently of mean blood pressure (BP). However, in real world clinical practice, this phenomenon is frequently considered as random fluctuation. This review aimed to investigate the differences among studies investigating visit-to-visit BPV and CVD using electronic health record (EHR) and clinical trial data. Our review suggests that BP values in clinical trial data are derived using a stricter protocol compared to EHR data. Furthermore, there was no consensus on metrics used in estimation of BPV.
Related Concept Videos
Factors affecting Blood pressure
Physiological Factors:
Errors occurring during blood pressure monitoring
Several factors...
Measurement of Blood Pressure
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Variability: Analysis
The range is a simple measure of variability, indicating the difference between the highest and...
Hypertension and Regulation of Blood Pressure

