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Homogeneous Glycoconjugate Produced by Combined Unnatural Amino Acid Incorporation and Click-Chemistry for Vaccine Purposes
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Author Correction: Proof of concept for a single-dose Group B Streptococcus vaccine based on capsular polysaccharide

Filippo Carboni1, Roberta Cozzi1, Giacomo Romagnoli1

  • 1GSK, Siena, Italy.

NPJ Vaccines
|January 25, 2024
PubMed
Abstract

No abstract available in PubMed .

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Vaccinations

Overview
Conjugated Proteins02:50

Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...