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Targeted Cancer Therapies

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Updated: Jul 4, 2025

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

Unlocking Early Cancer Detection: Exploring Biomarkers, Circulating DNA, and Innovative Technological Approaches.

B Krishna Prasanth¹, Saad Alkhowaiter², Gaurav Sawarkar³

¹Department of Community Medicine, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, IND.

|January 26, 2024

Summary

Early cancer detection using biomarkers and liquid biopsies significantly improves patient outcomes. Advancements in circulating DNA analysis and artificial intelligence enhance diagnostic accuracy and risk assessment for better treatment.

Keywords:

biomarkers biopsy cancer early detection early symptoms

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Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients

Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients

Published on: September 9, 2020

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Automatic Separation and Collection of Cancer-Related Substances from Clinical Samples

Published on: January 13, 2023

Area of Science:

Oncology
Biochemistry
Medical Diagnostics

Background:

Early cancer diagnosis is critical for effective treatment and prevention.
Biomarkers provide essential information on cellular changes from healthy to malignant states.
Advancements in identifying circulating tumor DNA and cells are crucial for early detection.

Purpose of the Study:

To review developments in early cancer diagnosis.
To evaluate indicators for early cancer detection, medical condition assessment, and risk evaluation.
To highlight the importance of early identification for prognosis and treatment success.

Main Methods:

Review of ongoing developments in biomarkers for early diagnosis.
Analysis of circulating DNA for diagnostic purposes.
Exploration of liquid biopsies, imaging, established tumor markers, plasma DNA technologies, gender differences, and artificial intelligence (AI) in diagnosis.

Main Results:

Biomarkers and circulating DNA technologies are key to identifying cancer-specific mutations.
Patient delay in seeking medical attention impacts early diagnosis.
AI and advanced imaging show promise in improving diagnostic capabilities.

Conclusions:

Early cancer detection through advanced biomarkers and diagnostics is vital for improving patient prognosis.
Understanding early symptoms and reducing diagnostic delays are critical.
Continued research in liquid biopsies and AI can further enhance early cancer identification and management.