[Histologic varieties of adeno-squamous cancer of the endometrium]

Adenosquamous carcinoma of the endometrium combines glandular and squamous cell tumour structures. It is advisable to distinguish well- and poorly differentiated variants of adenosquamous carcinoma (ASC). Well-differentiated ASC is characterized by the intraglandular growth of squamous cell structures in the form of pseudopapillae and has a favourable prognosis (5-year survival rate is 88%). Squamous cell structures of poorly differentiated ASC involve the myometrium in line with the glandular component and this variant has an unfavourable prognosis (5-year survival rate in 45%).