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Colorectal Neoplasia in Asian Americans Undergoing First Time Asymptomatic Average-risk Screening Colonoscopies
Brendan Chen1,2, Katie Hsia1, Kirsten Loscalzo3
1Department of Medicine.
Journal of Clinical Gastroenterology
|January 26, 2024
Summary
Asian Americans have a substantial prevalence of colorectal neoplasia, similar to White individuals. However, they are less likely to develop sessile serrated polyps but more likely to develop left-sided tubular adenomas.
Area of Science:
- Gastroenterology
- Oncology
- Epidemiology
Background:
- Asian Americans represent a rapidly growing US demographic with limited data on colorectal neoplasia.
- Understanding neoplasia characteristics in this population is crucial for targeted screening.
Purpose of the Study:
- To determine the prevalence and subtypes of colorectal neoplasia in Asian Americans undergoing screening colonoscopies.
- To compare neoplasia characteristics between Asian and White patients.
Main Methods:
- A cross-sectional study analyzed 2208 index colonoscopies (2015-2020) in average-risk Asian and White patients.
- Polyp histopathology was retrospectively classified, and univariate/multivariate analyses identified risk factors.
Main Results:
- Overall prevalence of colorectal neoplasia was similar between Asian (44.2%) and White (43.5%) patients.
- Asians were less likely to have sessile serrated polyps (5.5% vs. 9.9%) but more likely to have left-sided tubular adenomas (22.6% vs. 18.0%) compared to Whites.
Conclusions:
- Colorectal neoplasia prevalence is significant in Asian Americans, necessitating enhanced screening promotion.
- Quality metrics for colorectal cancer screening may require adjustments for demographic factors like race, particularly regarding sessile serrated polyp detection.
