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A new function for nuclear lamins: providing surface tension to the nuclear drop

Richard B Dickinson1, Tanmay P Lele2,3,4

  • 1Department of Chemical Engineering, University of Florida, 1030 Center Drive, Gainesville, FL, 32611, USA.

Current Opinion in Biomedical Engineering
|January 29, 2024
PubMed
Summary

The nuclear lamina, a thin structure, acts like a liquid drop surface, providing tension that controls nuclear shape and deformation in migrating cells. This nuclear drop model explains how lamins maintain nuclear integrity and function.

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