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Published on: November 22, 2013
Levofloxacin-Induced Hepatotoxicity in Patients With Legionnaires' Disease: Implications and Management
Mohamed Ismail1, Nishi Parikh2, Merry Zhai2
1Medicine, Rutgers University New Jersey Medical School, Newark, USA.
Abstract:
Legionnaires' disease (LD), caused by the Legionella bacterium, primarily manifests as pneumonia and could result in a spectrum of clinical severity. As treatment necessitates the use of antibiotics, levofloxacin, a fluoroquinolone, is a commonly preferred option due to its broad-spectrum activity. However, the potential side effects of levofloxacin, including rare instances of hepatotoxicity, introduce a therapeutic challenge. This case report explores the association between levofloxacin and hepatotoxicity and its implications for treating LD.
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