Emerging Lipid-based Carriers for Systematic Utilization in the Pharmaceutical and Biomedical Sciences: A Review

Area of Science:

• Pharmaceutical Sciences
• Biomedical Sciences
• Drug Delivery Systems

Background:

• Lipid-based carriers are innovative systems revolutionizing drug delivery.
• They offer improved solubility, stability, and targeted delivery of therapeutic agents.
• Liposomes, lipid nanoparticles, and solid lipid nanoparticles are key examples.

Purpose of the Study:

• To review the contribution of emerging lipid-based carriers in pharmaceutical and biomedical sciences.
• To highlight their advantages in drug delivery and potential for precision medicine.

Main Methods:

• Review of current literature on lipid-based drug delivery systems.
• Analysis of the properties and applications of various lipid carriers.
• Discussion of advancements in tailoring carriers for targeted delivery.

Main Results:

• Lipid-based carriers can encapsulate diverse drug types (hydrophilic and hydrophobic).
• They exhibit biocompatibility and biodegradability, reducing toxicity.
• Tailorable properties allow for enhanced cellular uptake, controlled release, and targeted delivery to specific tissues like tumors.

Conclusions:

• Emerging lipid-based carriers address critical drug delivery challenges, enhancing stability, bioavailability, and targeted delivery.
• These systems hold significant potential to revolutionize disease treatment and improve patient outcomes.
• Continued research promises more sophisticated carriers for advanced precision medicine.