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Effects of SGLT2 Inhibitors and DPP-4 Inhibitors on Advanced Glycation End Products

Masataka Kusunoki1, Fumiya Hisano2, Shin-Ichi Matsuda3

  • 1Department of Diabetes, Motor Function and Metabolism, Research Center of Health, Physical Fitness and Sports, Nagoya University, Nagoya City, Aichi, Japan.

Drug Research
|January 29, 2024
PubMed
Summary

Sodium glucose cotransporter 2 (SGLT2) inhibitors significantly reduced advanced glycation end products (AGEs), a risk factor for cardiovascular disorders, in type 2 diabetes patients. Dipeptidyl peptidase-4 (DPP-4) inhibitors did not show this effect.

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