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A Three-year Retrospective Study Looking at Preventing Hospital Acquired Thrombosis
Vipin Kammath1, Anuj Gupta2, Alexander Bald1
1Department of Surgery, Queen Elizabeth Hospital NHS Foundation Trust, Gateshead, UK.
Cardiovascular & Hematological Agents in Medicinal Chemistry
|January 30, 2024
Summary
Hospital-acquired deep vein thrombosis (HA-DVT) affects vulnerable patients. While risk assessments are high, nearly a quarter of HA-DVT cases received inappropriate prophylaxis doses, highlighting areas for improvement in patient care.
Area of Science:
- Medical research
- Clinical epidemiology
- Public health
Background:
- Hospital-acquired venous thromboembolism (HA-VTE) is a significant cause of preventable death in hospitals.
- Effective VTE prophylaxis, guided by risk assessment, is crucial for patient safety.
- National programs aim to standardize and improve VTE prevention strategies in healthcare settings.
Purpose of the Study:
- To identify and analyze hospital-acquired deep vein thrombosis (HA-DVT) cases at a specific hospital.
- To evaluate the quality and adherence to VTE preventative measures.
- To identify opportunities for reducing HA-DVT incidence and improving patient outcomes.
Main Methods:
- Retrospective cohort study utilizing electronic health records from April 2019 to April 2022.
- Defined HA-DVT cases based on positive ultrasound doppler reports and timing relative to hospital admission.
- Assessed VTE prophylaxis quality, including risk assessment completion, appropriate dosing, and discharge prescriptions.
Main Results:
- VTE risk assessment completion exceeded the national benchmark at 98.5%.
- 135 HA-DVT cases were identified; 16 lacked prescribed prophylaxis, with documented reasons in 11.
- 23% of HA-DVT cases received weight-inappropriate prophylaxis doses, and 31% had active malignancy.
Conclusions:
- The hospital demonstrates high compliance with VTE risk assessment protocols.
- Suboptimal dosing of thromboprophylaxis and omissions in prophylaxis were observed in a notable proportion of HA-DVT cases.
- HA-DVT disproportionately impacts vulnerable patients and remains associated with significant mortality, necessitating continued vigilance and improvement in preventative strategies.
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